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流感病毒的分子進化

作者:記者:通訊員:攝影: 出處:發布時間:2008-10-13

時間:2008.10.14上午830

地點:動物科技學院2#302房間

報告人簡介:

劉文軍,研究員、博士生導師。1996年畢業于美國佛羅里達大學,分子和細胞生物學專業,獲博士學位;1996-2000年分別于美國Oklahoma大學醫學中心和美哈佛休斯醫學研究所從事科學研究;2000-2004年任美國GENZYME 公司高級科學家和美國醫療資源有限公司副總裁;2004年入選中國科學院“百人計劃”,并獲百人計劃擇優支持。現任中國科學院微生物研究所分子病毒中心主任,中日聯合實驗室主任等職。目前主持973、十一五支撐計劃等多項國家級課題及國際合作項目,主要致力于動物病毒分子進化、禽流感病毒跨種間傳播機制以及新型抗病毒藥物的研究。

Selected Publications:

1.         Qin Z, Sun L, Ma B, Cui Z, Zhu Y, Kitamura Y, Liu W.F#. F gene recombination between genotype II and VII Newcastle disease virus. Virus Research. 2008 Feb;131(2):299-303.

2.         Sun L, Zhang GH, Jiang JW, Fu JD, Ren T, Cao WS, Xin CA, Liao M, Liu WJ#. A Massachusetts prototype like coronavirus isolated from wild peafowls is pathogenic to chickens. Virus Research. 2007 Dec;130(1-2):121-8.

3.         Yang LM, Xue QH, Sun L, Zhu YP, Liu WJ#. Cloning and characterization of a novel feline IFN-omega. Journal of Interferon Cytokine Research. 2007 Feb;27(2):119-27.

4.         Yang LM, Zhao LZ, Hu RL, Shi ZS, Liu WJ#.A novel double-antigen sandwich enzyme-linked immunosorbent assay for Measurement of Antibodies against rabies virus. Clinical Vaccine Immunology. 2006 Aug;13(8):966-8.

5.         Jinhua Liu, Haixia Xiao, Fumin Lei, Qingyu Zhu, Kun Qin, Xiaowei Zhang, Xinglin Zhang, Deming Zhao, Guihua Wang, Youjun Feng, Juncai Ma, Wenjun Liu, Jian Wang, George F. Gao. Highly pathogenic H5N1 influenza virus infection in migratory birds. Science. 2005,309:5738.

6.         Liu, W.-J., Petier M.R .and Hansen, P. J. (1999) Binding of Ovine Uterine Serpin to Lymphocytes. American Journal of Reproductive Immunology. 41:428.

7.         Ramachdran, R., Nollert M. U., Qiu, H., Liu, W-J., Cummings, R. D., Zhu, C., and McEver, R. P. (1999) Tyrosine replacement in P-selectin glycoprotein ligand-1 affects distinct kinetic and mechanical properties of bonds with P-and E-selectin. Proceedings of National Academy of Sciences of the United States of America. 96:13771.

8.         Liu, W.-J., Ramachdran, R., Kang, J., Cummings, R. D., McEver, R. P. (1998) Identification of N-terminal residues on P-selectin glycoprotein ligand-1 required for binding to P-selectin. Journal of Biological Chemistry. 273:7078.

9.         Liu, W.-J., Gottshall, S. L., and Hansen, P. J. (1997) Increased expression of cell surface markers on / TCR+ intraepithelial lymphocytes by the local presence of the conceptus. American Journal of Reproductive Immunology. 37:199

10.     Liu, W.-J., and Hansen, P. J. (1995) Progesterone-induced secretion of a soluble form of dipeptidyl peptidase IV (CD26) by the uterine endometrium of the ewe and cow that costimulates lymphocyte proliferation. Endocrinology. 136:779

 

 

 

 

 

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